Senior Bioinformatics Scientist, (San Diego/Southern CA/Remote)

Remote Full-time
Invivoscribe is an industry pioneer and global leader in precision oncology diagnostics. For more than 30 years we have driven international standardization of molecular and flow cytometry testing and expanded access to advanced cancer therapies worldwide. Our mission is simple and unwavering: Improving Lives with Precision Diagnostics®

We are seeking toadd a Senior Bioinformatics Scientist. The Senior Bioinformatics Scientist is a hands-on technical leader with advanced knowledge of scientific principles and concepts who designs, builds, and validates production-grade bioinformatics software and scalable NGS pipelines (on-prem and cloud) to diagnose and track disease (MRD) for clinical and research applications. This role independently identifies opportunities, defines technical roadmaps, and leads delivery from requirements and design through implementation, verification/validation, release, and lifecyclesupport.

Headquartered in San Diego, with operations across North America, Europe, and Asia, Invivoscribe develops and manufactures a comprehensive portfolio of molecular and flow cytometry assays, reagents, controls, and bioinformatics tools under ISO 13485 design control. Our products and services support more than 700 clinical laboratories in over 160 countries.

Core Responsibilities
• Lead the design and development of bioinformatics software and pipelines to support Whole Genome Sequencing (WGS), hybrid-capture, and amplicon based NGS assays.
• Work in close collaboration with the R&D and clinical lab teams, representing bioinformatics from a technical leadership role.
• Evaluate and develop novel methods and external tools; perform benchmarking and method comparisons, and document recommendations and decisions; own projects end-to-end.
• Develop reproducible, testable bioinformatics software using modern engineering practices (git, code review, unit/integration tests, CI/CD, containerization), and workflow technologies (e.g., Nextflow).
• Apply deep Next Generation Sequencing (NGS) analytics expertise and partner with scientific stakeholders to translate bioinformatics outputs into actionable conclusions.
• Lead bioinformatics software development for CAP/CLIA/NYA environments, including requirements definition, design documentation, verification and validation planning/execution, traceability, change control, and release documentation.
• Provide technical leadership across cross-functional teams and influence others to raise team standards (R&D, clinical labs, QA/RA, DevOps).

Core Requirements
• Ph.D. degree in bioinformatics, computational biology, molecular biology, or related field with, typically, 8+ years applicable post-graduate experience. M.S. degree in bioinformatics or related field and 10+ years of applicable post-graduate experience. Equivalent combination of education and experience may be considered.
• Advanced proficiency with Linux and strong programming skills (Python, bash required; additional languages welcome).
• Experience building and/or leveraging AI agents and LLMs for various tasks and optimization of software development.
• Demonstrated experience designing and building production bioinformatics pipelines for WGS/WTS assays.
• Hands-on experience developing and operating bioinformatics software in the cloud, including workflow execution at scale and management of compute/storage costs.
• Experience collaborating across multi-disciplinary teams and providing technical leadership through influence (with or without direct reports).
• Strong foundation in statistics and quantitative analysis of biological datasets.
• Extensive background in immunology or cancer research is highly preferred.
• Experience developing software in a regulated environment is a plus (e.g. IVD, IVDR, CAP/CLIA/NYS).
• Proficient computer skills and good working knowledge of Microsoft Office programs and collaboration tools (Word, Outlook, Teams, Excel and PowerPoint) and the ability to learn new software programs.

Why Join Us

At Invivoscribe, You Will Join a Mission-driven Global Organization Advancing The Future Of Precision Oncology. You Will Have The Opportunity To Shape Major Scientific And Commercial Partnerships That Impact Patients Around The World. We Offer
• Competitive compensation and performance incentives
• Comprehensive global benefits
• A collaborative, innovative-driven culture
• The opportunity to make a significant global impact in precision medicine

Invivoscribe is an Equal Opportunity Employer.

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