[Hiring] Principal Bioinformatics Scientist @6451 Roche Sequencing Solutions, Inc.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description This role involves supporting the development of Roche Diagnostics Molecular Assays that have a global impact on patient care. • Collaborate with multidisciplinary teams of molecular and computational biologists, as well as wet lab scientists, to design, optimize, and troubleshoot advanced high-throughput sequencing assays and workflows for clinical diagnostic applications. • Contribute bioinformatics expertise throughout the assay development lifecycle, including initial sequencing, validation, and production implementation, by developing and maintaining analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples. • Create, implement, and streamline bioinformatics tools and workflows in partnership with wet lab scientists to enhance assay development efficiency and data quality. • Provide hands-on troubleshooting to ensure data quality, integrity, and accessibility across the diagnostic workflow, while addressing the needs of internal and external stakeholders through scientific and business analyses. • Advocate for best practices in documenting, training, and scaling algorithms, tools, and workflows to ensure reproducibility and scalability. • Clearly communicate project outcomes and team progress across various teams and organizational functions to promote alignment and collaboration. Qualifications • PhD or Master’s degree in Bioinformatics, Computational Biology, Statistics, or a related field. • 4+ years of industry experience in clinical diagnostics or a related domain. • Expertise in DNA/RNA sequencing data analysis and interpretation. • Proficient in programming skills in R and/or Python, with experience working in a distributed Linux environment. • Proficient in creating clear, insightful visualizations of complex biological data, with strong presentation skills to effectively communicate results to both technical and non-technical audiences. • Strong understanding of molecular biology principles and hands-on familiarity with next-generation sequencing laboratory processes. • Able to work closely with bench scientists to troubleshoot experimental and workflow issues. • Skilled in writing and maintaining bioinformatics workflows using workflow management systems such as Snakemake or Nextflow. • Demonstrated ability to independently develop informatics solutions and contribute to scientific informatics initiatives. • Solid understanding of cancer biology and in vitro diagnostics (IVD). Requirements • Proficiency in C++ or Java is a plus. Benefits • Discretionary annual bonus may be available based on individual and Company performance. • This position qualifies for the benefits detailed at the link provided below. Apply tot his job