Director, in vivo Pharmacology

Genesis Therapeutics is seeking a director-level candidate responsible for leading the in vivo pharmacology team. A successful candidate will have extensive experience leading in vivo PK/PD and efficacy studies both internally and externally to enable drug discovery and development against cancer, autoimmune and other disease areas. The candidate should have a track record of being the pharmacology lead for small molecule drug discovery projects and successfully guiding the generation of compelling in vivo data packages. This key position will be based in San Diego, CA.Responsibilities- Identify and access appropriate in vivo models for oncology, inflammatory and autoimmune disease indications.- Conceptualize, design, and guide the execution of in vivo studies performed both internally and externally.- Develop strategies to demonstrate utility of inhibitors in relevant in vivo disease models. Assemble data packages.- Manage and mentor a small internal in vivo pharmacology team.- Collaborate closely within a Project Team environment to achieve drug discovery goals and objectives.- Clearly and concisely present hypotheses, strategies, and project progress at interdisciplinary team meetings.- Author and oversee IACUC protocols to ensure high ethical compliance. Contribute to the preparation of regulatory submissions.Qualifications- Extensive industry experience and proven success leading in vivo pharmacology efforts, using a rigorous and creative approach to scientific problem solving, as evidenced by publications and a record of accomplishment.- Minimum of 6 years in pharmacology, preferably with experience in both large pharma and small biotech organizations.- Substantial familiarity working with contract research organizations and academic collaborators.- Strong technical expertise in in vivo biology, including PK/PD and efficacy studies with deep understanding of oncology and/or inflammatory modelsOutstanding written and verbal communication, organizational and interpersonal skills.

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