Senior/Executive Medical Director, Global Clinical Development

Position: Senior/Executive Medical Director, Global Clinical DevelopmentDepartment: Translational ScienceLocation: Remote with up to 20% global and domestic travelReports To: Senior Vice President, Head of Translational SciencePosition SummaryAngitia Biopharmaceuticals, a science-driven biotech company dedicated to developing breakthrough therapies for musculoskeletal diseases, is seeking an experienced Senior/Executive Medical Director of Global Clinical Development. This role provides strategic leadership and oversight of global clinical programs and is central to executing our late-stage clinical strategies, with a focus on Phase 2 and Phase 3 development for rare pediatric bone disorders. The ideal candidate will bring deep clinical and scientific expertise in rare pediatric bone disorders, with a strong foundation in endocrinology, and a proven ability to lead pivotal global trials in rare disease settings. Strong leadership experience is essential, including the ability to lead cross-functional teams in a fast-paced, collaborative environment, and effectively represent the company at key scientific engagements.ResponsibilitiesProvide strategic medical leadership across global clinical development programs in musculoskeletal and skeletal rare diseases, with particular focus on pediatric bone disorders.Lead the design, execution, and oversight of late-stage clinical development programs (Phase 2 and Phase 3), ensuring scientific rigor, patient safety, and regulatory compliance.Design and oversee innovative clinical trial protocols, ensuring alignment with regulatory standards and commercial objectives.Lead cross-functional clinical teams, including medical monitors, clinical operations, biostatistics, and regulatory affairs, to ensure timely and high-quality trial execution.Serve as medical lead for interactions with global regulatory agencies, including strategic planning for regulatory submissions, responses, and key milestone meetings (e.g., End-of-Phase 2, pre-NDA).Provide scientific and clinical input for the development of study protocols, investigator brochures, clinical study reports, scientific publications, and regulatory documents.Maintain strong engagement with Key Opinion Leaders (KOLs) in pediatric bone disease and skeletal endocrinology to support study design and program direction.Represent the company in global forums, including scientific conferences and advisory boards.Actively contribute to the long-term clinical development roadmap and lifecycle management of investigational assets.QualificationsMD or MD/PhD with board certification in endocrinology, pediatric endocrinology, or a related field, with a minimum of 10 years of clinical development experience in the biotech or pharmaceutical industry.Prior success in global trial management and regulatory interactions in the U.S, EU, and other major markets preferred.Proven track record in rare disease clinical development, especially in pediatric bone disorders (e.g., hypophosphatasia, osteogenesis imperfecta, X-linked hypophosphatemia).Successful track record of managing global studies and contributing to regulatory submissions (IND through BLA/NDA).Deep understanding of endocrine mechanisms impacting bone and mineral metabolism.Experience interacting with regulatory authorities on a global scale.Experience leading multidisciplinary clinical teams in a fast-paced, collaborative environment.Proven leadership with strong communication and team-building skills.Salary Range:$250,000 to $310,000About AngitiaEstablished in June 2018, Angitia Biopharmaceuticals is a clinical-stage biotechnology company focused on the discovery and development of innovative therapeutics for serious musculoskeletal diseases. Angitia is currently studying 3 biologic product candidates in the clinic for the treatment of osteoporosis (Phase 2), osteogenesis imperfecta (OI) (Phase 1), and spinal fusion (Phase 3). Leveraging the team's extensive experience and scientific acumen in novel drug development, Angitia is committed to providing groundbreaking therapies to satisfy key unmet medical needs. The founder and the core team members of Angitia are seasoned scientific leaders in new drug discovery, development, and management from both overseas and domestic large multinational companies. The company has built an organization with offices in Westlake Village, CA and Guangzhou, China that is distinguished by world-class scientists with talents that are proficient in the pathophysiology of musculoskeletal diseases. We utilize cutting-edge technologies of genetics and molecular biology to uncover new mechanisms, signal transduction pathways and their interactions combined with computer aided drug design to identify new drug targets, and to discover and develop new biological and small molecule medicines. The company is committed to serving patients in need by carrying out innovative science including internal research and external collaborations with academics and global biopharmaceutical companies. We are seeking talented individuals who are innovative, ambitious, and great team players to join our vibrant group.Learn more at www.angitiabio.com.Benefits:Medical, dental, and vision coverage for employees and their eligible dependents401(K) Retirement Plan with Company matchCompany paid Long Term Disability CoverageCompany-paid life Insurance ADD CoverageVoluntary Life Insurance ADD CoverageEmployee Assistance Program (EAP)Company-paid HolidaysVacationPaid Sick LeaveTelecommunication Monthly StipendWork-From-Home Equipment ReimbursementOriginally posted on Himalayas

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