Senior Manager IT – Business Partner & Solutions Lead

Sionna Therapeutics is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for CF by developing novel medicines that normalize the function of the CFTR protein. Sionna’s goal is to deliver differentiated medicines for people living with CF that can restore their CFTR function to as close to normal as possible by directly stabilizing CFTR’s nucleotide-binding domain 1 (NBD1), which the company believes is central to potentially unlocking meaningful improvements in clinical outcomes and quality of life for people with CF. Leveraging over a decade of the co-founders’ extensive research on NBD1, the company is advancing a pipeline of novel small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in NBD1. Sionna is also developing a portfolio of complementary CFTR modulators that are designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Position Summary: Sionna Therapeutics is seeking a Senior Manager IT – Business Partner & Solutions Lead who will help design, implement, and manage Sionna’s Enterprise data integration approach. This individual will serve as a technical systems enabler and process optimizer, responsible for building a practical and scalable approach for data connectivity between our enterprise and SaaS platforms, serving as the primary BP for G&A capabilities. The successful candidate will bring a strong understanding of cloud-first enterprise architecture, SaaS ecosystems, and data integration frameworks and capabilities. They will combine technical expertise with business acumen to deliver impactful solutions that enhance collaboration and reduce manual effort across Sionna’s growing organization. This individual will also develop, advance, and oversee Sionna selection and usage of productivity tools such as Smartsheet, LucidChart, and OnePager, and will also be a key contributor to Sionna’s approach and usage of AI. Responsibilities: • Design, implement, and maintain data and system integrations between core enterprise and SaaS platforms (e.g., M365, NetSuite, Paylocity, Agiloft, etc.) to ensure seamless data flow and operational efficiency. • Develop and manage data automations and workflows using the to-be chosen platforms and approaches (e.g., Celigo, Workato, Power Automate, or similar). • Manage and support enterprise productivity tools that support cross-functional teams. • Partner with business stakeholders to analyze current processes, identify bottlenecks, and design technology-driven improvements. • Collaborate with Enterprise IT Operations to ensure that all integrations and tools align with security, compliance, and data governance standards (including GxP and SOX where applicable). • Support IT operational planning by helping prioritize integration and automation initiatives aligned with business goals. • Provide technical documentation and knowledge sharing for implemented systems and automations. • Stay informed about emerging tools and technologies that enhance productivity, integration, or collaboration, with a keen eye and as an advocate for AI. • Act as a catalyst for innovation, driving a culture of continuous improvement through automation and intelligent system design. Qualifications: • Bachelor’s degree or equivalent in Information Systems, Computer Science, or related field. • 7+ years of experience in IT systems, automation, or integration engineering within a biotech, pharmaceutical, or life sciences environment. • Proven experience building and maintaining system integrations using APIs, iPaaS and ETL platforms, or middleware. • Practical knowledge of cloud-based architectures (e.g., Azure, AWS, Google Cloud). • Understanding of data governance, compliance, and security standards, including Part 11 and ISO/NIST frameworks. • Experience with pure enterprise SaaS ecosystems. • Excellent communication skills, with the ability to translate technical solutions into clear business value. • Demonstrated ability to operate independently in a fast-paced, matrixed environment and collaborate effectively across teams. • Strong problem-solving, analytical, and organizational skills. • Exemplary service orientation with a proactive approach to improving user experience and system reliability. Preferred Skills/Experience: • Experience in implementing or supporting data workflow platforms like Celigo or Workato. • Familiarity with data visualization or analytics tools (e.g., Power BI, Tableau, Looker). • Working knowledge of enterprise automation orchestration and monitoring. • Background in ITSM/ITIL frameworks and enterprise MDM and ETL. • Experience with smaller scale ERP SaaS systems Salary Range: $130,000 – $160,000 Apply tot his job