Principal Scientist R&D

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. We are seeking a highly experienced and innovative Principal Scientist to join our team. The Principal Scientist will spearhead early-stage assay and device technology feasibility initiatives efforts and drive early development to enable assets more efficiently in Tempus's product portfolio and research offerings. This role will focus on front-end technical evaluations and development, emphasizing the exploration and assessment of emerging molecular chemistries and applications as well as a broad range of instrumentation and detection platforms. Additionally, this role will interface with bioinformatics and data teams to build workflows that aid in the development of AI applications and enable discoveries from complex data sets, including medical data, genomic data, metadata, population data, and multiomic data. Key Responsibilities: The Principal Scientist will be a high-level independent contributor with extensive experience in NGS and other molecular techniques and platforms. Additionally, the ideal candidate will be able to contribute meaningfully to multiomic technology evaluations in areas such as proteomics, metabolomics, imaging, instrumentation, and other life science-based testing and processing technologies. The Principle Scientist will also support bespoke research contracts with Pharma and Biotech customers/collaborators. Qualifications: Ph.D. in Molecular Biology, Biochemistry, Genetics, or a related field with 8+ years of experience in a relevant scientific role. Strong analytical and problem-solving skills, with the ability to design and execute complex experiments. Extensive expertise in NGS-related technologies and applications, including DNA/RNA library preparation and NGS platform knowledge. Direct experience with or working knowledge of several areas of multiomics, proteomics, metabolomics, imaging, instrumentation, and other life science-based technologies. Strong written and verbal communication skills to enable definitive feasibility outcomes relative to clearly defined business use cases. Ability to cross-functionally collaborate with a diverse set of scientific and operational teams to enable seamless technology transfers. Ability to mentor and advise scientific staff. #LI-GL1 #LI-Hybrid The expected salary range below is applicable if the role is performed from [Illinois] and may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits, depending on the position. Illinois Pay Range $107,000—$132,000 USD We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

Apply Now