MES (POMSNet)

Remote Full-time
Senior MES Engineer – POMS Net
Experience: 15+ YearsIndustry: Pharmaceutical / Life SciencesLocation: USA (Remote – must be USA‑based)
Role Summary
We are seeking a highly experienced Senior MES Engineer – POMS Net with deep pharmaceutical manufacturing expertise. The role will lead and support POMS Net MES design, implementation, integration, and lifecycle management across regulated manufacturing environments, ensuring full GxP and data integrity compliance.
Key Responsibilities

Lead POMS Net MES solution design, configuration, and deployment for pharma manufacturing sites
Act as SME for manufacturing execution, electronic batch records (EBR), workflows, and recipes
Drive end‑to‑end MES lifecycle activities including requirements, design, build, test, validation, deployment, and support
Collaborate with Manufacturing, QA, Automation, IT, and CSV teams
Support and lead computer system validation (CSV) activities in compliance with FDA, GxP, 21 CFR Part 11
Ensure data integrity (ALCOA+) and audit readiness
Manage MES integrations with ERP, LIMS, Historians, DCS/PLC systems
Troubleshoot complex MES issues and drive continuous improvement initiatives
Provide technical leadership, mentoring, and review of design documentation
Participate in regulatory inspections and internal audits as MES SME





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